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Abstract #4557

Theoretical and Experimental Benefits of Multi-Band (MB) EPI for pCASL Brain Imaging

Xiufeng Li 1 , Dingxin Wang 2 , Steen Moeller 1 , Kamil Ugurbil 1 , and Gregory Metzger 1

1 Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2 Siemens Medical Solutions USA Inc, Minneapolis, MN, United States

To achieve comprehensive insight into g-factor, leakage contamination and non-sequential slice acquisition order effects of MB EPI on ASL perfusion imaging, both imaging studies and theoretical evaluations were performed, indicating that even in the presence of inter-slice signal leakeage, MB EPI greatly benefits high-resolution whole brain ASL perfusion imaging with respect to both SNR efficiency and CBF quantification.

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