Moderate protein content does not influence on DWI-thermometry: Temperature-controlled Artificial CSF phantom study
Koji Sakai 1 , Ryusuke Nakai 1 , Kei Yamada 2 , Jun Tazoe 2 , Kentaro Aakazawa 2 , and Naozo Sugimoto 1
Kyoto University, Kyoto, Kyoto, Japan,
Prefectural University of Medicine, Kyoto, Japan
Among MR thermometry, the most clinically applicable may
be the post processing of diffusion-weighted images (DWI).
However, this DWI-based method might be influenced by
the composition of CSF, which can strongly affect its
viscosity and diffusivity. The purpose of this study was
to investigate the influence of protein content on DWI
thermometry by using temperature-controlled artificial
CSF (ACSF). The results of DWI thermometry were not
influenced by the protein content in the range of 0.0 to
8.01 mg/ml (approximately 40 times protein content of
normal adult) at near body temperature.
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