Abstract #4198
Presence of AVA in High Frequency Oscillations of the Perfusion fMRI Resting State Signal
Domenico Zac 1 , Uri Hasson 1,2 , Ben Davis 1 , Nicola De Pisapia 2 , and Jorge Jovicich 1,2
1
Center for Mind/Brain Sciences, University
of Trento, Mattarello, TN, Italy,
2
Department
of Psychology and Cognitive Sciences, University of
Trento, TN, Italy
The Amplitude Variance Asymmetry (AVA) of the BOLD
resting state signal has been demonstrated to provide
reproducible nonrandom patterns of high frequency
resting state activity. To investigate its neural,
vascular or hemodynamic sources we studied resting state
AVA from perfusion fMRI data. Perfusion-derived BOLD AVA
patterns replicated previous pure BOLD findings. A
significant CBF AVA pattern was also detected with
similar topological features but smaller spatial extent
than the BOLD AVA. These results suggest a neuronal
origin of these transients as CBF measurements are more
coupled with metabolism than BOLD measurements.
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