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Abstract #4102

Accuracy of multiparametric MRI for mapping prostate cancer by Gleason score

Maarten Leonard Smits 1 , Bruce L Daniel 2 , Sharon E. Clarke 2 , Jesse McKenney 2 , Andrew Wentland 2 , Manoj Saranathan 2 , Lewis Shin 2 , Kyung Sung 2 , Brian Hargreaves 2 , Emine U. Saritas 2 , Dwight G. Nishimura 2 , and Graham Sommer 2

1 University Medical Center Utrecht, Utrecht, Netherlands, 2 Stanford University, California, United States

This study assessed prospectively the ability of multiparametric (mp) MRI to map intraprostatic adenocarcinoma (Pca) of varying Gleason scores and the mapping accuracy of the individual components of mp-MRI. All sequences were much more accurate in imaging higher grades (significant tumor) than lower grade tumor. DWI and ADC maps were most accurate in imaging PCa overall, and DCE imaged higher grade tumor most accurately. T2W gave poorer results than either DWI or DCE. The multiparametric approach resulted in marginally better results than DWI in this study.

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