Accuracy of multiparametric MRI for mapping prostate cancer by Gleason score
Maarten Leonard Smits 1 , Bruce L Daniel 2 , Sharon E. Clarke 2 , Jesse McKenney 2 , Andrew Wentland 2 , Manoj Saranathan 2 , Lewis Shin 2 , Kyung Sung 2 , Brian Hargreaves 2 , Emine U. Saritas 2 , Dwight G. Nishimura 2 , and Graham Sommer 2
University Medical Center Utrecht, Utrecht,
University, California, United States
This study assessed prospectively the ability of
multiparametric (mp) MRI to map intraprostatic
adenocarcinoma (Pca) of varying Gleason scores and the
mapping accuracy of the individual components of mp-MRI.
All sequences were much more accurate in imaging higher
grades (significant tumor) than lower grade tumor. DWI
and ADC maps were most accurate in imaging PCa overall,
and DCE imaged higher grade tumor most accurately. T2W
gave poorer results than either DWI or DCE. The
multiparametric approach resulted in marginally better
results than DWI in this study.
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