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Abstract #4074

Evaluating water selective DWI of the breast: A test-retest study

He Zhu 1 , Lori Arlinghaus 1 , Jennifer G. Whisenant 1 , John C. Gore 1 , and Thomas Yankeelov 1

1 VUIIS, Vanderbilt University, Nashville, TN, United States

Diffusion weighted imaging (DWI) provides quantitative and non-invasive assessments of cell density in breast tissue. We recently developed a water selective DWI acquisition obviating the need for fat suppression using inversion recovery or pre-saturation. Instead, our method relies on image-based shimming to identify the water resonance during a pre-scan and then applies frequency selective excitation on the water resonance. In this abstract, we report a test-retest study to investigate if the added complexity of this water selective DWI method compromised reproducibility.

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