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Abstract #4019

PCr recovery rates of gastrocnemius medialis and soleus muscles at various exercise levels

Georg B Fiedler 1,2 , Albrecht Ingo Schmid 1,2 , Sigrun Goluch 1,2 , Elmar Laistler 1,2 , Kiril Schewzow 1,2 , Michael Wolzt 3 , Ewald Moser 1,2 , and Martin Meyerspeer 1,2

1 MR Centre of Excellence, Medical University of Vienna, Vienna, Vienna, Austria, 2 Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Vienna, Austria, 3 Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Vienna, Austria

Kinetics of phosphorus metabolites in human soleus (SOL) and gastrocnemius medialis (GM) muscles were measured during and after plantar flexion exercise bouts with varying workloads, using single-shot localized MRS (semi-LASER) at high time resolution with a custom multichannel 1H/31P coil at 7T. PCr recovery time τ was successfully quantified in GM and in SOL. In GM, τ showed positive correlation with exercise intensity and GM PCr depletion. In SOL, these correlations were not found, e.g. some datapoints with strong depletion in SOL even showed a τ of only 20s. pH in GM was also correlated to PCr depletion.

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