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Abstract #4003

Regional differences and age-related changes of apparent diffusion coefficient (ADC) in vertebral bone marrow of healthy adult.

RAYMOND LEE 1 , GLADYS LO GOH 1 , KA FAT JOHN CHAN 1 , Wing Wa Li 1 , PO LUNG CHAN 1 , CHI WAI LIU 1 , KA MAN CHAN 1 , and MEI LEE HUNG 1

1 DEPARTMENT OF DIAGNOSTIC & INTERVENTIONAL RADIOLOGY, HONG KONG SANATORIUM & HOSPITAL, HONG KONG, Hong Kong

Diffusion-weighted MRI imaging is an emerging technique to assess bone marrow abnormality. Normal values may need to adapt for age and anatomic location to avoid misinterpretation. Previous studies showed contradictory results whether bone marrow diffusivity changes with age and focus on lumbar region only. The purpose of this study was to evaluate the regional differences and age-related changes of ADC values in vertebral bone marrow by measuring ADC values in cervical, thoracic, lumbar, sacral and both iliac bone marrow in healthy adults. Current study may give an insight to establish the normal ADC values on vertebral column for future references.

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