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Abstract #3980

Three-Dimensional MRI-Based Statistical Shape Model of the Knee in Patients with ACL Injuries

Valentina Pedoia 1 , Drew Lansdown 2 , Paul Jung 1 , C. Benjamin Ma 2 , and Xiaojuan Li 1

1 Department of Radiology and Biomedical Imaging, UCSF, San Francisco, California, United States, 2 Department of Orthopedic Surgery, UCSF, San Francisco, California, United States

This study presents a novel 3D MRI-based method to analyze the knee bones shape and for the first time applied the technique to knees with ACL-injuries. A shape modeling is extracted for tibia and femur using a set of matched landmarks. Significant shape differences were found between ACL-injured and control knees at baseline, and significant differences are detected in longitudinal shape changes between ACL-injured and control knees. Bone shape quantification has the potential to identify specific risk factors for injuries and to describe novel imaging markers for the development of post-traumatic OA after an acute injury.

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