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Abstract #3975

Transcytolemmal Water-Exchange Slows in Infarcted Myocardium

James Goldfarb 1,2 and Wenguo Zhao 1

1 St Francis Hospital, Roslyn, NY, United States, 2 Program in Biomedical Engineering, SUNY Stony Brook, Stony Brook, NY, United States

We measured and compared the transcytolemmal cellular water exchange rates of fibrotic and viable myocardium in patients with chronic myocardial infarcts. Transcytolemmal water exchange rates differed between infarcted and viable myocardium. Viable myocardium can be assumed to be in fast exchange limit. Infarcted myocardium has significantly slower exchange which alters the linearity of contrast curve shapes.

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