Abstract #3931
Radiation-induced myocardial injury visualized by LGE-MRI
Brent D. Wilson 1,2 , Alexis Harrison 1,2 , Yu-Huei J. Huang 3 , Kavitha Damal 2 , Nathan S. Burgon 2 , Mark M. Haslam 2 , Martha J. Glenn 3 , David K. Gaffney 3 , Bill J. Salter 3 , Nassir F. Marrouche 1,2 , and Christopher J. McGann 1,2
1
Cardiovascular Center, University of Utah,
Salt Lake City, Utah, United States,
2
Comprehensive
Arrhythmia Research and Management Center, University of
Utah, Salt Lake City, Utah, United States,
3
Huntsman
Cancer Institute, University of Utah, Salt Lake City,
Utah, United States
Recent advances in LGE-MRI technology allow us to
visualize and quantify the extent of myocardial tissue
injury after external beam radiation therapy (EBRT) for
treatment of cancer. We evaluated the utility of 3D late
gadolinium enhanced MRI to identify atrial injury
secondary to EBRT and the correlation between extent of
tissue damage and dose of EBRT administered. Cardiac MRI
identifies subclinical injury months after EBRT and also
shows a dose-dependent pattern of injury. Imaging
myocardial injury resulting from radiation using MRI may
be a useful modality to follow cardiac toxicity from
EBRT and identify individuals who are more susceptible
to CV radiation damage.
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