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Abstract #3903

Regional Myocardial Contractility In Thalassemia Major By Magnetic Resonance Tagging

Antonella Meloni 1 , Chiara Tudisca 2 , Emanuele Grassedonio 2 , Cristina Paci 3 , Alessandra Quota 4 , Petra Keilberg 1 , Vincenzo Positano 1 , Massimo Midiri 2 , Massimo Lombardi 1 , and Alessia Pepe 1

1 CMR Unit, Fondazione G.Monasterio CNR-Regione Toscana and Institute of Clinical Physiology, Pisa, Italy, 2 Policlinico "Paolo Giaccone", Istituto di Radiologia, Palermo, Italy, 3 Centro Trasfusionale, Ospedale S Maria alla Gruccia, Montevarchi, Italy, 4 Serv. Talassemia, Osp. "V. Emanuele III", Gela, Italy

Compared to healthy subjects, patients with thalassemia major (TM) have a significant lower cardiac contractility, assessed by means of MR tagging techniques. However in TM the altered contractility is not related to cardiac iron, volumes and global function.

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