Abstract #3720
High-resolution localized 2D J-resolved Spectroscopy for Biological Tissues
Yuqing Huang 1 , Zhiyong Zhang 1 , Shuhui Cai 1 , and Zhong Chen 1
1
Department of Electronic Science, Xiamen
University, Xiamen, Fujian, China
Localized 2D J-resolved spectroscopy (JRES) enables the
complete separation of chemical shift and J coupling
information along two different dimensions, which
provides a useful tool for assignment of overlapped
resonances in metabolite detection of biological
tissues. However, conventional 2D JRES approaches
usually suffer from field inhomogeneous effects due to
macroscopic magnetic susceptibility in biological
tissues. In this report, a new pulse sequence based on
intermolecular double-quantum coherences (iDQCs) is
presented to achieve high-resolution localized 2D
J-resolved information for studying metabolites in
biological systems, even for in vivo applications.
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