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Abstract #3717

Multivoxel Proton Spectroscopy for Non-invasive MR Thermometry: phantom comparison of PRESS and semiLASER-localized chemical shift imaging for temperature monitoring

Seena Dehkharghani 1 , Li Wei 2 , Hui Mao 1 , John N Oshinski 1 , and Deqiang Qiu 1

1 Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, 2 Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, United States

The validity of single-voxel proton MRS techniques has been established for MR thermometry at discrete spatial positions. Multivoxel techniques may however permit the collection of spatial temperature gradients non-invasively, but have not been thoroughly evaluated for this purpose. We propose to compare standard 2D-multivoxel PRESS to single-voxel techniques in a phantom study of MR thermometry. As our preliminary experience has suggested vulnerabilities to chemical shift misregistration and limited MRS quality at excitation margins with standard multivoxel techniques, we further propose comparison with a more recently introduced semiLASER-localized CSI, offering theoretical benefits over 2D CSI in this phantom study.

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