Dual echo based referenceless thermometry for MRgFUS applications

Thermal monitoring in Magnetic Resonance guided Focused Ultrasound (MRgFUS) treatments is a crucial step where the phase images from MR images are used to get thermal maps. One of the widely used techniques is PRF shift technique that involves some form of image subtraction using a baseline pre-treatment image. Subject motion and tissue deformation due to coagulation can severely distort these techniques. Self-referenced methods [1] help to overcome this hurdle where the baseline phase in the region-of-interest (ROI) is estimated using the data available outside the hot zone (ROI) and subtracted with actual phase to get the thermal maps. In this work a new technique is described, where the baseline phase inside the ROI is estimated using the data acquired from two echos and their phase difference outside ROI. This method not only eliminates the need for baseline subtraction but also produces better results as the reference echo used in generating the model is acquired along same location

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