Abstract #3696
Intraoperative assessment of cerebrovascular reserve capacity during tumor resection with BOLD fMRI
Marco Piccirelli 1 , Oliver Bozinov 2 , Jan-Karl Burkhardt 2 , Roman Kocian 3 , Marian C. Neidert 2 , Antonios Valavanis 1 , Luca Regli 2 , Athina Pangalu 1 , and Jorn Fierstra 2
1
Neuroradiology, University Hospital Zurich,
Zurich, ZH, Switzerland,
2
Neurosurgery,
University Hospital Zurich, ZH, Switzerland,
3
Anesthesiology,
University Hospital Zurich, ZH, Switzerland
Cerebrovascular reserve capacity (CVR) is a useful
clinical risk assessment tool for ischemia. Application
to brain tumors has a very interesting potential due to
the correlation between increased vascularity and tumor
malignancy. Further, intraoperative CVR mapping should
impact on patient management and guide surgical
intervention, by assessing the effectiveness of surgery
for brain tumors inducing vascular remodeling. We
demonstrate the feasibility of CVR determination with MR
during surgical tumor resection on 8 anesthetized
patients and illustrate very different vascular
responses to surgery. Such spatial information helps to
better understand tumor hemodynamics and determine tumor
borders.
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