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Abstract #3681

MR-Guided Prostate Hyperthermia with a Commercial Endorectal HIFU Ablation Array

Eugene Ozhinsky 1 , Vasant A. Salgaonkar 2 , Chris J. Diederich 2 , and Viola Rieke 1

1 Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, 2 Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, United States

The goal of this project was to identify operational modifications, and assess the feasibility of delivering protracted MR-guided prostate hyperthermia with a commercial endorectal ablation array. Hyperthermia-specific sonications were imple-mented on ExAblate 2100 prostate phased array ablation system and performed on a tissue-mimicking phantom. Tem-perature monitoring was performed on a 3T MRI scanner using a spoiled gradient echo sequence. These experiments illustrate the ability to successfully employ hyperthermia specific beamforming to control the shape of energy deposition, to deliver long duration power output with the ExAblate 2100 prostate system, and to monitor the resulting heat generation with MR thermometry.

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