The high negative predictive value to pre-operative MRI in Grade I endometrial cancer in the clinical setting.
Erin Bravo 1 , Krupa Patel-Lippmann 2 , Kristie Guite 3 , Jessica Robbins 3 , David Kushner 2 , Ahmed Al-Niaimi 2 , and Elizabeth Sadowski 2
Radiology, University of Wisconsin, Madison,
Wisconsin, United States,
of Wisconsin, Wisconsin, United States,
University of Wisconsin, Wisconsin, United States
In grade 1 endometrial cancer there is debate whether or
not lymphadenectomy is necessary. Strong evidence exists
that women without myometrial or cervical invasion have
decreased risk of lymph node metastasis, thus may
potentially avoid lymphadenectomy. The goal of our study
was to evaluate myometrial and cervical invasion in
women with grade 1 endometrial cancer on preoperative
MRI when being read by abdominal radiologists compared
with surgical pathology. Our study determined the
negative predictive value of MRI in detecting myometrial
and/or cervical invasion is 96%, which may decrease the
need for lymphadenectomy in women with very low risk for
lymph node metastasis.
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