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Abstract #3637

Clinical Feasibility of Distortion Corrected Diffusion-Weighted (DW) Images of Human Cervix

Maysam Jafar 1 , Katherine Downey 1 , Sharon L Giles 2 , Veronica A Morgan 2 , Geoffrey S Payne 1 , and Nandita M DeSouza 1

1 Clinical Magnetic Resonance Unit, Institute of Cancer Research, Sutton, Surrey, United Kingdom, 2 Clinical Magnetic Resonance Unit, Royal Marsden Hospital, Sutton, Surrey, United Kingdom

DW sequences improve detection of cervical tumor but are prone to distortions, worse when using an endovaginal receiver coil. We corrected image distortions by acquiring forward and reverse gradient images and then used Chang&Fitzpatricks reverse gradient algorithm. Assessment of the correction by measuring the angle of the endocervical canal to the horizontal on corrected and uncorrected high b-value images showed significant differences in the former but not the latter when compared to measurements from T2-W images. Normalised cross-correlation using template matching to assess similarities between corrected/uncorrected DW and T2-W images varied marginally, indicating the need for feature tracking techniques.

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