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Abstract #3601

Diffusion-weighted STEAM MRS to measure fat unsaturation in regions with low fat content

Stefan Ruschke 1 , Thomas Baum 1 , Hendrik Kooijman 2 , Marcus Settles 1 , Axel Haase 3 , Ernst J. Rummeny 1 , and Dimitrios C. Karampinos 1

1 Department of Diagnostic and Interventional Radiology, Technische Universitt Mnchen, Munich, Germany, 2 Philips Healthcare, Hamburg, Germany, 3 Zentralinstitut fr Medizintechnik, Technische Universitt Mnchen, Garching, Germany

MR spectroscopy has been previously employed as a technique for estimating fat unsaturation. However, if the fat fraction is low and the water peak overlaps with the olefinic fat peak, the quantification of fat unsaturation can become challenging. Long-TE PRESS sequences have been suggested as a way to reduce the water peak and measure fat unsaturation. However, a TE of the order of 200 ms should be employed to reduce J-coupling effects, resulting in a low SNR. We present an alternative approach to measure fat unsaturation using a diffusion-weighted STEAM sequence, which is shown to be able to reduce the water peak at moderate TEs.

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