Abstract #3595
The Importance of consistent RF Spoiling for MRI based Liver Iron Content Determination with Signal Intensity Ratios preliminary data
Arthur Peter Wunderlich 1 , Volker Rasche 2,3 , Holger Cario 4 , Markus Juchems 1 , and Meinrad Beer 1
1
Dept. for Diagnostic and Interventional
Radiology, Univ.-Clinic Ulm, Ulm, Germany,
2
Experimental
Cardiovascular Imaging, Univ.-Clinic Ulm, Ulm, Germany,
3
Internal
Medicine II, Univ.-Clinic Ulm, Ulm, Germany,
4
Pediatry,
Univ.-Clinic Ulm, Ulm, Germany
Signal Intensity Ratio (SIR) between liver and reference
tissue (paraspinal muscle) has proven to be a reliable
method for determination of liver iron content (LIC).
However, we found that SIR values depend on activation
of RF spoiling. In a preliminary analysis, we determined
LIC with the method published by Gandonin data with and
without RF spoiling and compared these values to LIC
determined from the commercial Ferriscan method. Linear
correlation between both methods was performed and R
was evaluated. While we achieve a good R value without
RF spoiling, it was significantly worse with RF
spoiling.
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