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Abstract #3549

Non-contrast-enhanced free-breathing lung imaging using high-speed MRI data acquisition and phase dispersion analysis

Yu Li 1 , David Roach 1,2 , and Jason Woods 1,2

1 Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 2 Center for Pulmonary Imaging Research, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States

We developed a new non-contrast-enhanced lung imaging technique using high-speed dynamic data acquisition and phase dispersion analysis. By evaluating regional MRI phase dispersion of dynamic lung images during free breathing, image contrast may be generated from susceptibility changes in pulmonary parenchyma. We found that temporal behaviors of MRI phase dispersion may be used to investigate lung function by examining regional susceptibility changes dynamically in every respiration cycle. This offers a new imaging technique that has the potential to improve functional imaging of the lung.

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