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Abstract #3497

In vivo Quantitative Susceptibility Mapping of the Mouse Brain at 9.4T: A new contrast mechanism to investigate genetic models of neurodegeneration

James Martin O'Callaghan 1 , Jack Wells 1 , Karin Shmueli 1,2 , and Mark Lythgoe 1

1 Centre for Advanced Biomedical Imaging, UCL, London, UK, United Kingdom, 2 Medical Physics and Bioengineering, UCL, UK, United Kingdom

Quantitative susceptibility mapping(QSM) has been shown to be sensitive to iron concentrations in the brain as well as myelination of white matter. We present the first steps towards generating a QSM atlas of the invivo mouse brain for application in models of neurodegeneration.

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