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Abstract #3470

Dual language pathways associate with attention and language deficits in high-functioning autism: a diffusion spectrum imaging (DSI) study

Yu-Chun Lo 1 , Susan Shur-Fen Gau 2,3 , and Wen-Yih Isaac Tseng 1,3

1 Center for Optoelectronic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan, 2 Department of Psychiatry, National Taiwan University College of Medicine, Taipei, Taiwan, 3 Graduate Institute of Brain and Mind Sciences, National Taiwan University, Taipei, Taiwan

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with language-communication deficit as one of the core symptoms. Patients with high-functioning autism show worse performance than neurotypicals in complex language tasks such as comprehension and inference. According to previous studies, attention impairments are the key cognitive deficits leading to autism symptomatology, including language deficits. In this study, we found dual pathways involved not only language but also attention in ASD, suggesting that the roles of the dual pathways differ between neurotypicals and ASD.

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