Meeting Banner
Abstract #3431

Brain Diffussivity and Neurochemical Changes in Obstructive Sleep Apnea: A Pilot Correlation Study

Manoj Kumar Sarma 1 , Rajakumar Nagarajan 1 , Paul Michael Macey 2 , Ravi Aysola 3 , and M. Albert Thomas 1

1 Radiological Sciences, UCLA School of Medicine, Los Angeles, CA, United States, 2 School of Nursing, UCLA School of Medicine, Los angeles, CA, United States, 3 Division of Pulmonary and Critical Care Medicine, UCLA School of Medicine, Los Angeles, CA, United States

Obstructive sleep apnea (OSA) is a common disorder characterized by repeated hypoxic episodes during sleep. Cerebrovascular risk factors such as hypertension, diabetes mellitus, obesity can be offshoot of OSA. Advanced neuroimaging techniques, such as diffusion tensor imaging (DTI) and magnetic resonance spectroscopic imaging (MRSI) enable non-invasive and accurate identification of OSA-induced, structuralneurochemical changes. The goals of this study were to investigate changes in FA and MD between OSA patients and healthy controls and correlate the FA /MD values with metabolite ratios in various brain regions of OSA patients.

This abstract and the presentation materials are available to members only; a login is required.

Join Here