Meeting Banner
Abstract #3372

Improving the detection of white matter lesions in patients with Multiple Sclerosis with super-resolution

Daniel Garca-Lorenzo 1 , Benedetta Bodini 1,2 , Geraldine Bera 3 , Stephane Lehericy 4 , and Bruno Stankoff 1,5

1 ICM/CRICM, UPMC/INSERM UMR_975 CNRS UMR 7225, Paris, France, 2 Department of Neuroimaging, Institute of Psychiatry King's College London, London, United Kingdom, 3 APHP, Hpital Piti-Salptrire, Paris, France, 4 CENIR, ICM/CRICM, UPMC/INSERM UMR_975 CNRS UMR 7225, Paris, France, 5 APHP, Hpital Tenon, Paris, France

Multiple sclerosis lesions may affect brain atrophy measurements and this can be reduced with lesion inpainting. We propose to use a super-resolution technique to increase the resolution of T2-w images before segmenting lesions. Our hypothesis is that using super-resolution T2-w images, we detect more lesions and the inpainting will provide more accurate atrophy measures. We found a higher number of detected lesions using super-resolution compared with standard T2-w images. Also, super-resolution lesions masks reduced the error in the estimation of the cortical thickness compared to the 2D lesion masks after inpainting. This technique can be applied to already acquired protocols.

This abstract and the presentation materials are available to members only; a login is required.

Join Here