Abstract #3372
Improving the detection of white matter lesions in patients with Multiple Sclerosis with super-resolution
Daniel Garca-Lorenzo 1 , Benedetta Bodini 1,2 , Geraldine Bera 3 , Stephane Lehericy 4 , and Bruno Stankoff 1,5
1
ICM/CRICM, UPMC/INSERM UMR_975 CNRS UMR
7225, Paris, France,
2
Department
of Neuroimaging, Institute of Psychiatry King's College
London, London, United Kingdom,
3
APHP,
Hpital Piti-Salptrire, Paris, France,
4
CENIR,
ICM/CRICM, UPMC/INSERM UMR_975 CNRS UMR 7225, Paris,
France,
5
APHP, Hpital Tenon, Paris, France
Multiple sclerosis lesions may affect brain atrophy
measurements and this can be reduced with lesion
inpainting. We propose to use a super-resolution
technique to increase the resolution of T2-w images
before segmenting lesions. Our hypothesis is that using
super-resolution T2-w images, we detect more lesions and
the inpainting will provide more accurate atrophy
measures. We found a higher number of detected lesions
using super-resolution compared with standard T2-w
images. Also, super-resolution lesions masks reduced the
error in the estimation of the cortical thickness
compared to the 2D lesion masks after inpainting. This
technique can be applied to already acquired protocols.
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