Abstract #3370
Equilibrium Model for Magnetic Resonance Grading of Hippocampal Sclerosis in Temporal Lobe Epilepsy
Hassan Bagher-Ebadian 1,2 , Mohammad Reza Nazem-Zadeh 1 , Jason M Schawlb 3 , Abdelrahman Hassane 1 , and Hamid Soltanian-Zadeh 1,4
1
Radiology, Henry Ford Hospital, Detroit, MI,
United States,
2
Physics,
Oakland University, Rochester, MI, United States,
3
Neurosurgery,
Henry Ford Hospital, MI, United States,
4
CIPCE,
ECE Dept., University of Tehran, Tehran, Iran
Temporal lobe epilepsy (TLE) patients that are medically
refractory may be candidates for surgical intervention.
It is critical to select the surgery candidates
confidently to maximize the chance of
post-surgical-seizure freedom. The presence of sclerosis
in hippocampus is a good indicator for a positive
outcome of surgery. This study introduces a novel
approach (Equilibrium-Model) as a grader of sclerosis
severity in hippocampus using MR-Fluid Attenuation
Inversion Recovery (MR-FLAIR) information. The proposed
method is applied on MR-FLAIR information of ten TLE
patients with hippocampal sclerosis (pathology-proven).
Results (80% correct-classification-fraction) imply that
the proposed method may increase confidence in
localizing seizure focus.
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