Abstract #3282
In-vivo Breast Microcalcification Detection via Susceptibility Weighted Imaging at 7T
Sergey Cheshkov 1,2 , Guillaume Gilbert 3 , Ivan Dimitrov 1,4 , Samantha By 5 , Joseph Rispoli 5 , Mary McDougall 5,6 , Steve Wright 5,6 , Stephen Seiler 2 , and Craig Malloy 1,2
1
Advanced Imaging Research Center, University
of Texas Southwestern Medical Center, Dallas, TX, United
States,
2
Radiology,
University of Texas Southwestern Medical Center, Dallas,
TX, United States,
3
Philips
Medical Systems, Montral, Qubec, Canada,
4
Philips
Medical Systems, Cleaveland, OH, United States,
5
Biomedical
Engineering, Texas A&M University, College Station, TX,
United States,
6
Electrical
Engineering, Texas A&M University, College Station, TX,
United States
Pre-invasive cancer
ductal
carcinoma in situ
(DCIS)
may frequently be missed by the clinical dynamic
contrast-enhanced MRI. DCIS has been shown to strongly
associate with particular microcalcifications
distributions and patterns. Susceptibility weighted
imaging (SWI) has been proposed as a non-invasive
radiation-free alternative to mammography for early
detection of DCIS-associated breast microcalcifications
(diamagnetic), providing better localization and 3D
morphology. However, the desired high spatial resolution
is not feasible on the 1.5T and 3T systems due to the
long acquisition times. Benefiting from higher
susceptibility effects and gain in SNR we demonstrate
ultra-high resolution 7T SWI
in
vivo
for
calcification detection.
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