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Abstract #3213

Robust B 1 -Insensitive Whole-Brain T 1 Mapping with 3-TI MP-RAGE: Validation and Acquisition Strategy

Ives R Levesque 1,2 , Manojkumar Saranathan 1 , Thomas Tourdias 1,3 , Jason Su 1,4 , James A Rioux 1 , and Brian K Rutt 1

1 Radiology, Stanford University, Stanford, CA, United States, 2 Medical Physics, Oncology and RI-MUHC, McGill University, Montreal, QC, Canada, 3 Department of Neuroradiology, Bordeaux University Hospital, Bordeaux, France, 4 Electrical Engineering, Stanford University, Stanford, CA, United States

Fast T 1 mapping is of interest notably for segmentation of brain structures and myelin imaging. Whole-brain, high-resolution T 1 maps can be obtained from 3 MP-RAGE images with carefully selected inversion times in a clinically relevant time and free from B 1 heterogeneity effects. In this work, we validated the method for in vivo human applications, and compared the accuracy and blur of the 3-TI-MP method for different k-space ordering and parallel imaging factors. Our results show high accuracy and improved map quality from a 2D-centric k-space ordering scheme.

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