Abstract #3202
Efficient Imaging Parameters for Quantitative 3D T1rho Mapping of the Brain
Casey P. Johnson 1 , Daniel R. Thedens 1 , and Vincent A. Magnotta 1
1
Radiology, University of Iowa, Iowa City,
IA, United States
Quantitative T1ρ mapping has tremendous potential to
probe a variety of brain diseases. However, T1ρ mapping
has largely been limited to 2D single-slice
acquisitions. 3D mapping would be a major advance to
provide high spatial resolution maps of the entire
brain, but acquisition time is a significant challenge.
Here we simulate tradeoffs of imaging parameters for
recently-described rapid segmented 3D T1ρ mapping
sequences to determine which sets of parameters provide
the shortest acquisition times to achieve target T1ρ
precision thresholds. This is a critical step toward
fulfilling the need to efficiently acquire 3D T1ρ maps
of the brain.
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