Meeting Banner
Abstract #3200

Optimizing single component DESPOT using a Cramer-Rao Lower Bound framework

Rui Pedro A. G. Teixeira 1,2 , Shaihan J. Malik 1,3 , and Joseph V. Hajnal 1,3

1 Division of Imaging Sciences and Biomedical Engineering, King's College London, London, London, United Kingdom, 2 Institute of Biophysics and Biomedical Engineering, Faculty of Sciences, Lisbon, Lisbon, Portugal, 3 Centre for the Developing Brain, King's College London, London, London, United Kingdom

The Driven Equilibrium Single Pulse Observation of T1 & T2 (DESPOT) relaxometry technique aims to provide high quality 3D maps of T1 and T2 within a clinical time frame. We propose an optimization method built on the Cramr-Rao Lower Bound to guarantee low estimation standard deviation over a defined range of relaxation times and use it to design optimal single compartment DESPOT acquisitions for adult and neonatal brain.

This abstract and the presentation materials are available to members only; a login is required.

Join Here