Meeting Banner
Abstract #3167

A B 1 Insensitive qMT Protocol

Mathieu Boudreau 1 , Nikola Stikov 1 , and G. Bruce Pike 1,2

1 Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada, 2 Hotchkiss Brain Institute, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada

Quantitative magnetization transfer (qMT) requires several additional measurements to correct for instrumental biases (B 0 , B 1 ) and to constrain parameters in the fitting model (T 1 ). When using variable flip angle (VFA) T 1 maps, B 1 is used twice before fitting the qMT parameters: to correct T 1 , and the MT saturation powers. Inaccuracies in B 1 would propagate to the fitting of the qMT parameters through two pathways through errors in T 1 and MT saturation powers. This work demonstrates that for the Sled and Pike qMT model, certain qMT parameters (F, T 2f ) are insensitive to a large range of B 1 inaccuracies when using VFA.

This abstract and the presentation materials are available to members only; a login is required.

Join Here