Abstract #3133
Which one is most accurate and has highest precision? - A comprehensive analysis of T 2 (*) estimation techniques
Ferdinand Schweser 1 , Ines Krumbein 1 , Karl-Heinz Herrmann 1 , Hans-Joachim Mentzel 2 , and Jrgen R Reichenbach 1
1
Medical Physics Group, Institute of
Diagnostic and Interventional Radiology I, Jena
University Hospital - Friedrich Schiller University
Jena, Jena, Germany,
2
Section
Pediatric Radiology, Institute of Diagnostic and
Interventional Radiology I, Jena University Hospital -
Friedrich Schiller University Jena, Jena, Germany
MR relaxation parameters are often used to quantify the
state of tissue and to distinguish pathological from
normal conditions. MR magnitude noise can introduce a
serious bias toward higher or lower relaxation
parameters. Such a bias may have serious clinical
consequences, e.g., when relaxation parameters are used
for treatment decisions such as in liver iron overload
diseases. With the current contribution, we aim to give
clear recommendations how to estimate relaxation rates
for different experimental scenarios, such as in slow
and fast relaxing tissues.
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