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Abstract #3117

Identification of whole brain correlation patterns between resting-state fMRI signal amplitude and EEG vigilance in eyes-closed and eyes-open conditions

Chi Wah Wong 1 , Valur Olafsson 1,2 , Omer Tal 1 , and Thomas Liu 1

1 Center for Functional MRI, University of California San Diego, La Jolla, CA, United States, 2 Neuroscience Imaging Center, University of Pittsburgh, PA, United States

A prior study has shown that the global signal amplitude in resting-state fMRI is negatively correlated with a measure of EEG vigilance in the eyes-closed (EC) condition but not in the eyes-open (EO) condition. In this study, we used simultaneous EEG-fMRI to identify brain regions in which the BOLD signal amplitudes are correlated with EEG vigilance. We then compared the spatial distribution between the EC and EO conditions. We found that the BOLD signal amplitude in the motor cortex, middle temporal gyrus, basal ganglia and cuneus are more negatively correlated with EEG vigilance in EC than EO.

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