Postoperative Brain Tumor Resting State and Task fMRI Study for Radiotherapy Planning

For studying integration of fMRI into radiotherapy planning, rest and finger tapping scans were acquired on a tumor patient. Glioblastoma multiforme and surgical cavity were near the motor cortex. We hypothesized that resting state could complement information gathered during task. The data was analyzed and registered using tools provided by FSL. On the unaffected hemisphere motor areas overlapped, whereas the affected hemisphere motor area was only easily recognizable from resting-state. Tumor's proximity to activation region sometimes complicates the identification. Resting state might be able to give information not otherwise available. This study will be further validated with larger patient sample.

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