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Abstract #3049

Spatial dynamics separates higher order from primary resting state networks

Ashish Anil Rao 1 , Ek Tsoon Tan 2 , Rakesh Mullick 1 , and Suresh Emmanuel Joel 1

1 General Electric Global Research, Bangalore, Karnataka, India, 2 General Electric Global Research, New York, United States

Investigation and understanding of both intra and inter-subject variability of functional connectivity metrics is critical to be able to use it meaningfully in research and the clinic. Here we report an investigatoin of intra and inter-subject reproducibility of functional networks obtained using spatial ICA. We find that higher-order networks and primary networks have different characteristics of reproducibility and may have implications for their use in studying state, trait or disease.

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