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Abstract #2955

Metabolic response to a neuroinflammatory challenge in a model of Alzheimer's disease

Henryk Faas 1 , Maria Yanez Lopez 1 , Samira Parhizkar 2 , Stacey Knapp 2 , Dorothee Auer 1 , and Marie Christine Pardon 2

1 Clinical Neurosciences, University of Nottingham, Nottingham, Nottingham, United Kingdom, 2 Life Sciences, University of Nottingham, Nottingham, Nottingham, United Kingdom

Neuroinflammation plays a key role in a wide range of brain disorders, including stroke, Parkinsons, and Alzheimers disease (AD). Using MR spectroscopy, we investigate the differential metabolic response of the brain to a standard neuroinflammatory challenge, comparing an AD mouse model with normal controls.

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