Abstract #2895
Optimisation of asymmetric adiabatic pulses for single voxel metabolite cycled 1 H-MRS in the human brain at 9.4 Tesla
Ioannis Angelos Giapitzakis 1 , Tingting Shao 1 , Nikolai Avdievich 1 , Roland Kreis 2 , and Anke Henning 1,3
1
Dept. of High-Field Magnetic Resonance, Max
Planck Institute for Biological Cybernetics, Tbingen,
Baden-Wrttemberg, Germany,
2
Departments
of Radiology and Clinical Research, University of Bern,
Bern, Switzerland,
3
Institute
for Biomedical Engineering, University and ETH Zrich,
Zrich, Switzerland
Asymmetric adiabatic pulses have been used for
metabolite cycled 1H-MRS at 3 Tesla and 7 Tesla enabling
better spectral resolution and post-processing of the
measured data without scan time prolongation. In this
abstract, the frequency excitation profile of the
adiabatic pulses was extensively studied with regards to
time duration, the B
1
+
field
and the frequency sweep range. Optimum values for the
characteristics of the inversion pulses were found for
implementation in a STEAM sequence at 9.4T. Both phantom
and
in
vivo
measurements
on a healthy volunteer verified the simulations and
showed that metabolite cycled 1H-MRS is feasible at
9.4T.
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