Meeting Banner
Abstract #2792

Suppression of unwanted resonances in hyperpolarized MR studies with neat [1- 13 C]lactic acid

Cornelius von Morze 1 , Peder EZ Larson 1 , Hong Shang 1 , and Daniel B Vigneron 1

1 Dept. of Radiology & Biomedical Imaging, UCSF, San Francisco, CA, United States

Similar to pyruvate, neat [ 13 C]lactic acid appears to be the best form of lactate for dissolution DNP. Unfortunately the neat acid is prone to form a lactide dimer which overlaps spectrally onto product alanine. We investigated the use of a spectrally selective pre-saturation pulse sequence to eliminate dimer signal prior to hyperpolarized metabolic experiments in vivo.

This abstract and the presentation materials are available to members only; a login is required.

Join Here