Abstract #2748
Evaluation of Vascular Transfer Constants using Dynamic T1-Mapping during Contrast Agent Administration
Uwe Klose 1 , Sotirios Bisdas 1 , Herbert Kstler 2 , and Johannes Tran-Gia 2
1
Department of Diagnostic and Interventional
Neuroradiology, University Hospital of Tbingen,
Tbingen, Germany,
2
Institute
of Radiology, University of Wrzburg, Wrzburg, Germany
A new fast T1 mapping method, based on the acquisition
of 1000 single radial trajectories within a time of 6 s,
allows the direct observation of T1 changes during DCE
measurements. A single slice of a patient with a primary
brain lymphoma was examined. In four regions, the
dynamic T1 values were evaluated and Patlak plots were
calculated, using the signal in the superior sagittal
sinus to estimate the plasma concentration C
p
(t).
K
trans
values could be estimated as slopes of
fitted straight lines in the Patlak plot. Remarkably low
residuals between data points and fitted lines were
found.
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