Meeting Banner
Abstract #2735

Brain blood volume assessment using DCE in comparison to DSC methods

Moran Artzi 1,2 , Guy Nadav 1,3 , Gilad Liberman 1 , Orna Aizenstein 1 , and Dafna Ben Bashat 1,4

1 Functional Brain Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2 Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 3 Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel, 4 Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel

Cerebral blood volume (CBV) obtained using DSC is an important parameter for brain tumor assessment. DCE can also be used to extract blood plasma volume (Vp). This study investigated the relationship between DSC-CBV and DCE-Vp. A high correlation between cerebral DCE-Vp and DSC-CBV was detected in 22 healthy subjects. In three patients with brain tumors, similar maps were obtained with values above the threshold of 1.75, indicating malignant tumors. These results suggest DCE as preferable to DSC for blood volume assessment; this method has high spatial resolution, is less sensitive to susceptibility artifacts and provides additional information regarding tissue permeability.

This abstract and the presentation materials are available to members only; a login is required.

Join Here