Abstract #2702
Spin labeling MRI with Look-Locker readout for improved portal venous perfusion quantification
Marijn van Stralen 1 , Hanke Schalkx 2 , Nicky H.G.M. Peters 2 , Wouter Veldhuis 2 , Maarten S Van Leeuwen 2 , Maurice A.A.J. van den Bosch 2 , Josien P.W. Pluim 1 , and Esben T. Petersen 2
1
Image Sciences Institute, University Medical
Center, Utrecht, Netherlands,
2
Radiology,
University Medical Center, Utrecht, Netherlands
Spin labeling (SL) MRI of the liver has not yet been
widely investigated. Previously used single time point
readout does not take bolus arrival time differences
into account, hampering quantification. Therefore,
SL-MRI with Look-Locker (LL) readout was investigated
with pulsed and pseudo-continuous labeling strategies in
healthy volunteers. We found regional and intersubject
differences in bolus arrival time. Hepatic SL-MRI with
LL readout could successfully quantify portal venous
perfusion, with both labeling strategies, and was
comparable to flow-based perfusion.
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