Abstract #2686
The anisotropic component of diffusion improves visualisation of fiber tracts in the presence of oedema
Lawrence Kenning 1 , Martin Lowry 2 , and Lindsay W Turnbull 2,3
1
Centre for Magnetic Resonance
Investigations, University of Hull, Hull, East Riding of
Yorkshire, United Kingdom,
2
Centre
for Magnetic Resonance Investigations, Hull York Medical
School at the University of Hull, Hull, East Riding of
Yorkshire, United Kingdom,
3
Hull
and East Yorkshire Hospitals NHS Trust, East Riding of
Yorkshire, United Kingdom
DTI can visualise fiber tracts for surgery, however,
oedema and tumour infiltration cause FA to decrease. We
investigated the anisotropic component of diffusion to
visualise fiber tracts in the presence of oedema. Glioma
patients were scanned twice with DTI. ADC, FA and q maps
were generated. Percentagewise changes of q following
altered levels of oedema were reduced when compared to
those of FA. Increased values of ADC are destructive to
FA values given the normalisation process which q does
not include. Anisotropic component of diffusion maps
continue to show fiber tract directionality in the
presence of large amounts of oedema.
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