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Abstract #2682

Correlations between different sources of contrast at 9.4T: diffusion vs. susceptibility

Yohan van de Looij 1,2 , Nicolas Kunz 2 , Rajika Maddage 2 , Rolf Gruetter 2,3 , Petra S Hppi 1 , and Stphane V Sizonenko 1

1 Division of Child Growth and Development, University of Geneva, Geneva, GE, Switzerland, 2 Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fdrale de Lausanne, Lausanne, VD, Switzerland, 3 Department of Radiology, University of Geneva and Lausanne, Geneva and Lausanne, GE and VD, Switzerland

Diffusion Tensor Imaging (DTI) and Quantitative Susceptibility Mapping (QSM) are two MR techniques given a superb contrast between white and grey matter in the brain. Diffusivity and anisotropy of water in the tissues are derived from DTI whereas QSM is based on the magnetic susceptibility distribution. The aim of this work was to investigate the potential cross correlations between DTI and QSM in the rat brain white matter at ultra-high magnetic field. In addition to the effect of magnetic field orientation and myelin, we suggest an effect of axonal diameter/compaction to the QSM contrast.

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