Abstract #2636
Exchange and T2-relaxation effects in double pulsed field gradient experiments
Casper Kaae Snderby 1 , Henrik Lundell 1 , and Tim B. Dyrby 1
1
Danish Research Centre for Magnetic
Resonance, Copenhagen University Hospital, Hvidovre,
Denmark
Double Pulsed Field Gradient sequences have recently
been used to detect novel tissue contrasts such as the
Apparent Exchange Rate and Compartment Eccentricity. We
compare the effects of compartmental specific
T2-relaxation in both single and double pulsed field
gradient sequences. We measure a decrease in the
Apparent Diffusion Coefficient as either the mixing time
or the echo time is increased indicating filtering of
compartment specific signal components with fast
diffusivities. Our results indicate that both single and
double pulsed field gradient sequences should adopt for
the same TE in all experiments to maintain the relative
T2-relaxation weighting of the individual compartments.
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