Abstract #2553
High-Resolution Diffusion Tensor Imaging (DTI) of the Human Kidneys using a Free-Breathing Multi-Slice Targeted-FOV Approach
Rachel W Chan 1 , Constantin von Deuster 2,3 , Christian T Stoeck 2 , Jack Harmer 3 , Sebastian Kozerke 2,3 , and David Atkinson 1
1
University College London, London, London,
United Kingdom,
2
University
and ETH Zurich, Zurich, Zurich, Switzerland,
3
King's
College London, London, London, United Kingdom
Fractional anisotropy (FA) obtained by diffusion tensor
imaging (DTI) can be used to non-invasively assess
kidney function. A multi-slice targeted FOV technique
that uses a non-coplanar application of excitation and
refocusing pulse was extended to free-breathing kidney
DTI with a navigator-triggered technique. The purpose of
this study was to obtain high-resolution FA and
diffusion-tensor maps in healthy subjects who were
scanned with two (dual- and single-kidney) targeted FOV
scans. The FA maps showed consistency between the two
targeted FOVs and across subjects. The medulla and
cortical FA values, quantified over multiple contiguous
slices, were well-differentiated.
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