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Abstract #2477

Assessment of Aortic Stenosis Severity using Bayesian Multipoint Phase-Contrast MRI

Christian Binter 1 , Alexander Gotschy 1,2 , Robert Manka 1,2 , Simon H. Sndermann 3 , and Sebastian Kozerke 1,4

1 Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2 Dept. of Cardiology, University Hospital Zurich, Zurich, Switzerland, 3 Division of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland, 4 Imaging Sciences and Biomedical Engineering, King's College London, London, United Kingdom

The classification of aortic stenosis severity using Doppler sonography is based on the velocities across the valve and does not necessarily reflect the additional workload of the heart. Phase-Contrast MRI offers the possibility of quantifying the energy dissipated in turbulent flow and thereby potentially providing an objective measure of disease severity. Results from 16 patients and 10 age-matched controls are presented and compared to conventional diagnostic parameters determined by Doppler sonography. To analyze robustness, inter- and intra-observer variability analysis is performed.

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