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Abstract #2430

Estimation of shear modulus in heart phantom using FE-simulated and MRE-measured displacements

Samad Javid 1 , David Lake 1 , Shivaram Poigai 1 , Arvin Arani 1 , Armando Manduca 1 , Kiaran McGee 1 , Richard Ehman 1 , Dan Dragomir-Daescu 1 , and Philip Araoz 1

1 Mayo Clinic, Rochester, MN, United States

Cardiac MRE may be able to measure the regional myocardial shear stiffness. We used Finite Element (FE) technique to simulate a noise-free displacement filed in the myocardial wall of a polymeric heart phantom. MRI was used to measure the displacement field in the heart phantom. DI and LFE were then used to estimate the shear modulus in the phantom using the FE simulated and MR measured displacement data. Both inversion methods underestimated the shear modulus in the myocardial wall. The results showed that in thin walled structures, DI and LFE give better estimations of shear modulus at higher frequencies.

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