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Abstract #2376

Comparison of distributed parameter and Fermi modelling of cardiac MR perfusion with CT perfusion in coronary artery disease versus invasive coronary angiography

Giorgos Papanastasiou 1,2 , Michelle Williams 2 , Mark Dweck 2 , Saeed Mirsadraee 1 , Nick Weir 3 , Shirjel Alam 2 , Colin Stirrat 2 , David Newby 1,2 , and Scott Semple 1,2

1 Clinical Research Imaging Center, University of Edinburgh, Edinburgh, Lothian, United Kingdom, 2 Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, Lothian, United Kingdom, 3 NHS Medical Physics, University of Edinburgh, Edinburgh, Lothian, United Kingdom

My PhD focuses in modeling and quantification of myocardial blood flow (MBF) using dynamic contrast enhanced magnetic resonance (DCE-MRI) which can potentially be used for the diagnosis and prognosis of coronary artery disease and also the assessment and/or planning of therapy and intervention. Furthermore, I work in a multimodality cross-validation study of MBF using DCE-MRI, computed tomography perfusion and positron emission tomography perfusion in patients with coronary artery disease. Clinically, we aim to overcome critical limitations of individual techniques and use the merits of each technique to gain a better understanding of MBF at the clinical setting.

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