Abstract #2369
CHRONOLOGICAL CARDIAC MRI ASSESSMENT OF CIRCUMFERENTIAL AND LONGITUDINAL STRAIN FOLLOWING MECHANICAL OBSTRUCTION OF CORONARY MICROVESSELS IN PRE-EXISTING INFARCT
Maythem Saeed 1 , Mohammed SA Suhail 1,2 , Loi Do 1 , Steve W. Hetts 1 , and Mark W. Wilson 1
1
Radiology and Biomedical Imaging, University
of California, San Francisco, San Francisco, California,
United States,
2
Radiology,
University of California, San Diego, San Diego,
California, United States
The main processes that are responsible for acute and
chronic mechanical changes in the left ventricle (LV)
post-acute myocardial infarction (AMI) include
resolution of transitive natural progression of AMI and
long-term mechanical changes (contraction/relaxation and
dyssynchrony). This study was designed to monitor and
compare biventricular circumferential and longitudinal
strain/strain rate in large animals subjected to
infarction. Time resolved cine and tagged MRI have high
specificity in monitoring circumferential and
longitudinal strain changes over the course of weeks
after myocardial infarction in left and right
ventricles. MRI also showed the interaction between LV
and RV dysfunction in acute and chronic infarct.
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