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Abstract #2352

Fast Double-Echo EPI Pulse Sequence for Thermal Focal Spot Localization During MR-guided Regional Hyperthermia Treatment

Tetiana Dadakova 1 , Johanna Gellermann 2 , Otilia Voigt 2 , John Matt Pavlina 1 , and Michael Bock 1

1 Medical Physics, Department of Diagnostic Radiology, University Medical Center Freiburg, Freiburg, Germany, 2 Department of Radiation Oncology, University Hospital Tbingen, Tbingen, Germany

Regional hyperthermia is used as a supplementary therapy during cancer treatment to improve chemotherapy and radiotherapy effect. The temperature of the cancerous and healthy tissue is typically monitored with temperature probes inserted into catheters. MR thermometry with the proton resonance frequency method allows for a non-invasive temperature monitoring, and often conventional gradient echo techniques (FLASH) are used to measure the phase changes during heating. In this work, a double echo segmented EPI sequence (DEPI) for MR thermometry during hyperthermia was developed. The higher acquisition speed of DEPI can be exploited to localize unwanted thermal focal spots in the body of the patient, which can make the hyperthermia procedure safer and more reliable.

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